Pharmaceutical Analysis

One of the main goals of pharmaceutical Analysis is to ensure the quality, safety, and efficacy of pharmaceuticals via theoretical and practical teaching. This is the mission of the Department of Pharmaceutical Analysis. This department is equipped with cutting-edge equipment and qualified faculty, making it appropriate for teaching and research in the modern day. The department’s goals are to teach students how to apply analytical techniques in compliance with drug regulatory affairs, emphasise the value of method validation, and teach them how to develop quality assurance and control protocols in compliance with GMP, GLP, and cGMP guidelines. The department routinely instructs students on how to use the official pharmacopoeias to set standards for pure pharmaceuticals and formulations.The department features sophisticated Instruments in its well-maintained laboratories, and it also has a central instrumentation room with cutting-edge analytical equipment available. For routine instruction and research, tools such as gas chromatography, atomic absorption spectrometers, fluorescence spectroscopy, ultra fast liquid chromatography, Fourier transform infrared spectroscopy, UV spectrophotometers, polari metres, flame photometers, sonicators, rotary flash evaporators, refractive index, and statistical software are used. The department seeks to focus on bio analytical method development, particularly pharmacokinetic, bioavailability, and bioequivalent studies utilising animal models. The department is currently engaged in applied research, such as method development for API and formulations. The department’s goal is to become a centre of excellence for regulatory affairs and drug quality assurance and control.

Dr. Shebina P Rasheed

Professor & HOD

Mrs. Fathima Shahla K

Assistant Professor

Mr. Sanjay B

Assistant Professor

Mr. Sujith Unnikrishnan

Assistant Professor

Mrs. Ananya V M

Assistant Professor

Mrs. Sreelekha P P

Assistant Professor

M. pharm Pharmaceutical Analysis
M. pharm Pharmaceutical Quality Assurance

Pharmaceutical Analysis is a team of experienced faculty and students offering pharmaceutical analysis consultancy services to the pharmaceutical industry, research institutions, and startups. Our expertise lies in analytical method development, validation, and testing to ensure compliance with regulatory requirements.

Services

Can help Industry/Research/PG students in Development of stability indicating methods for Analysis of APIs/FPs using HPLC/UFLC for formulations and Bulk drugs
Drug Compatibility studies can be performed with Polymers, colorants preservatives and coating materials for API in formulation using FTIR
Volatile Oil identification and Quantification can be performed using Gas Chromatography
Heavy metals and Minerals like Lead, Cadmium and iron can be identified and quantified by Atomic Absorption Spectrophotometer
Fluorescence spectroscopical studies for Research and Projects can be performed by Spectrofluorimeter
Reaction Kinetics and Reaction products for synthetic Chemistry and herbal extraction can be performed using FTIR
Impurity Profiling can be carried out by UFLC/UV Visible Spectrophotometer
Analytical Method Development as per ICH Guidelines can be performed by UFLC, GC
Spectrofluorimeter and UV Visible Spectrophotometer
Intentionally added Corticosteroids in Herbal/Natural products can be identified by FTIR
Sodium, Potassium and calcium in samples and biological fluids can be identified and Quantified by Flame Photometer.

Book Chapters

NK Drishya,SS Prasanth, V Akhila, K Sruthi.”An Advanced Study on Development and Validation of RP HPLC Method for Simultaneous Estimation of Mesalamine and Prednisolone in Bulk and Formulation”. Technological Innovation in Pharmaceutical Research, BP International, 2019, pp. 108 - 115.
K Kamarunisa, P Deepthi Bhaskar, C Radhika, SS Prasanth.” Pharmacological Evaluation of the Wound Healing Activity of Cinnamommum Verum in Experimental Rats”. Current Aspects in Pharmaceutical Research and Development, Asian Publishers, 2019, pp. 101-107

Patents

Patent Title: Neuroprotective Effect of Taurine Hybrid for the Treatment of Neurodegenerative Disorders
Patent Application Number : 202241059343 A
Date of filling : 17/10/2022
Granted on : Patent Number :

Publications

Sujith Unnikrishnan.et.al, design and optimization strategies of PROTACs and its application, comparisons to other targeted protein degradation for multiple oncology therapies, Bioorganic chemistry, volume 154, January 2025.
Dr.Prasanth SS.et.al, Analytical methods to estimate the amount of additives in Confectioneries,GJRA 13(3), March 2024.
Sreelekha P Pavithran.et.al, A novel stability indicating UV Spectroscopic method for simultaneous estimation of Azelnidipine and Chlorthalidone in its pure and pharmaceutical dosage form, Indian drugs 60(11), November 2023.
Sreelekha P Pavithran.et.al, Forced degradation study of Rosuvastatin and Tenelegliptin, characterization of its degradation products by various analytical technique: A review, IJPSR 14(9), September 2023.
Sarath Prasanth, S.V., Magesh, N.S., Jitheshlal, K.V. et al. Evaluation of groundwater quality and its suitability for drinking and agricultural use in the coastal stretch of Alappuzha District, Kerala, India. Appl Water Sci 2, 165–175 (2012).
A.K. Azeem, C Dilip, SS Prasanth, V Junise Hanan Shahima, Kumsr Sajeev, C. Naseera, Anti–inflammatory activity of the glandular extracts of Thunnus alalunga, Asian Pacific Journal of Tropical Medicine, Volume 3, Issue 10, 2010, Pages 794-796,ISSN1995-7645,https://doi.org/10.1016/S1995-7645(10)60190-3.
Prasanth SS, Aiyalu R. Quantitative Determination of Cerberin in Seed Extract of Cerbera odollam and Rat Serum by High Performance Thin Layer Chromatography. J App Pharm Sci, 2015; 5 (Suppl 3): 061-069.
Rasheed A, Mounika P, Azeem AK, Prashanth SS. Development and validation of Silodosin in tablet formulation by various UV spectrophotometric methods. Inventi Rapid: Pharm Analysis & Quality Assurance. 2013 Feb 25.
Azeem AK, Dilip C, Prasanth SS, Shahima VJ, Sajeev K, Naseera C. Anti-inflammatory activity of the glandular extracts of. Thunnus alalunga. 2010.
Prasanth SS, Rajasekaran A. Visible spectrophotometric determination of cerberin in rat plasma. J App Pharm Sci, 2015; 5 (03): 109-112.
Prasanth SS, Rajasekaran A. Derivative ultra-violet spectroscopic method for the estimation of cerberin in rat plasma. Int. J. Pharma Bio Sci. 2015;6:749-58.
Sruthi K, Prasanth S, Kamarunnisa K, Drisya N, Ashyam K. FTIR-spectrophotometric analysis of levosulpiride and its pharmaceutical formulations. Int. J. Pharm. Chem. Anal. 2018;5:151-5.
Drisya NK, Prasanth SS, Akhila V, Sruthi K. An Advanced Study on Development and Validation of RP-HPLC Method for Simultaneous Estimation of Mesalamine and Prednisolone in Bulk and Formulation. Technological Innovation in Pharmaceutical Research Vol. 9. 2021 Jul 19:1-0.
SS Prasanth, AA Anjitha.. Q-ABSORBANCE RATIO AND VIERODT’S SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF FAMOTIDINE AND OMEPRAZOLE. IJPDA [Internet]. 2023Apr.4 [cited 2024Jan.31];11(1):9-16.